Welcome to Angel Water

Angel Water (Pty) Ltd was created to raise funds for Angelman Syndrome awareness. Although awareness is very important to us, so is giving back to our people, our community. We   supply   clean   purified   water.   We   believe   in   good   quality   and   respect   water   shortages   in   our   country.   There   are   several   companies   supplying   low   quality   water   but   we   guarantee   clean   high quality water  

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For every bottle of water bought Angel Water will donate R2 to Angelman Syndrome Awareness

Tel: 066 255 9594 Email:   info@angelwater.co.za  | orders@angelwater.co.za  

Angel   Water   (Pty)   Ltd   was   created   to   raise   funds   for   Angelman Syndrome   awareness.   Although   awareness   is   very   important to us, so is giving back to our people, our community. We   supply   clean   purified   water.   We   believe   in   good   quality   and respect    water    shortages    in    our    country.    There    are    several companies   supplying   low   quality   water   but   we   guarantee   clean high quality water  

Angelman   syndrome   is   a   genetic   disorder.   It   causes   developmental   disabilities,   neurological   problems   and sometimes, seizures. People with Angelman syndrome often smile and laugh frequently, and have happy, excitable personalities. Developmental    delays,    between    about    6    and    12    months    of    age,    are    usually    the    first    signs    of    Angelman syndrome. Seizures often begin between the ages of 2 and 3 years old. People   with   Angelman   syndrome   tend   to   live   a   normal   life   span,   but   the   disease   cannot   be   cured.   Treatment focuses on managing medical and developmental issues.

Angelman syndrome signs and symptoms include: • Developmental delays, including no crawling or babbling at 6 to 12 months • Intellectual disability • No speech or minimal speech • Difficulty walking, moving or balancing well (ataxia) • Frequent smiling and laughter • Happy, excitable personality People who have Angelman syndrome may also have other signs and symptoms, including: • Seizures, usually beginning between 2 and 3 years of age • Stiff or jerky movements • Small head size, with flatness in the back of the head (microbrachycephaly) • Tongue thrusting • Hair, skin and eyes that are light in color (hypopigmentation) • Unusual behaviors, such as hand flapping and arms uplifted while walking

Most   babies   with   Angelman   syndrome   don't   show   signs   or   symptoms   at   birth.   The   first   signs   of   Angelman syndrome are usually developmental delays, such as lack of crawling or babbling, between 6 and 12 months. If   your   child   seems   to   have   developmental   delays   or   if   your   child   has   other   signs   or   symptoms   of   Angelman syndrome, make an appointment with your child's doctor.

Angelman     syndrome     is     a     genetic     disorder.     It's     usually caused   by   problems   with   a   gene   located   on   chromosome   15 called the ubiquitin protein ligase E3A (UBE3A) gene. A missing or defective gene You   receive   your   pairs   of   genes   from   your   parents   —   one copy   from   your   mother   (maternal   copy)   and   the   other   from your father (paternal copy). Your   cells   typically   use   information   from   both   copies,   but   in   a small number of genes, only one copy is active. Normally,   only   the   maternal   copy   of   the   UBE3A   gene   is   active in   the   brain.   Most   cases   of   Angelman   syndrome   occur   when part of the maternal copy is missing or damaged. In   a   few   cases,   Angelman   syndrome   is   caused   when   two paternal   copies   of   the   gene   are   inherited,   instead   of   one   from each parent.

Angelman   syndrome   is   rare.   Researchers   usually   don't   know   what   causes   the   genetic   changes   that   result   in   Angelman   syndrome.   Most   people   with   Angelman   syndrome   don't   have   a   family   history   of the disease. Occasionally, Angelman syndrome may be inherited from a parent. A family history of the disease may increase a baby's risk of developing Angelman syndrome.

Complications associated with Angelman syndrome include: • Feeding   difficulties.    Difficulty   coordinating   sucking   and   swallowing   may   cause   feeding   problems   in   infants.   Your   pediatrician   may   recommend   a   high-calorie   formula   to   help   your   baby   gain weight. • Hyperactivity.    Children   with   Angelman   syndrome   often   move   quickly   from   one   activity   to   another,   have   a   short   attention   span,   and   keep   their   hands   or   a   toy   in   their   mouths.   Hyperactivity   often decreases with age, and medication usually isn't necessary. • Sleep   disorders.    People   with   Angelman   syndrome   often   have   abnormal   sleep-wake   patterns   and   need   less   sleep   than   most   people.   Sleep   difficulties   may   improve   with   age.   Medication   and behavior therapy may help control sleep disorders. • Curving of the spine (scoliosis). Some people with Angelman syndrome develop an abnormal side-to-side spinal curvature over time. • Obesity. Older children with Angelman syndrome tend to have large appetites, which may lead to obesity.

In   rare   cases,   Angelman   syndrome   may   be   passed   from   an   affected   parent   to   a   child   through   defective   genes.   If   you're   concerned   about   a   family   history   of   Angelman   syndrome   or   if   you   already   have a child with Angelman syndrome, consider talking to your doctor or a genetic counselor for help planning future pregnancies

Tel: 066 255 9594 Email: orders@angelwater.co.za 

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Tel: 066 255 9594 Email: orders@angelwater.co.za 

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